MolNFT v1 · #6160 · protein

The bacterial cell-division protein zipa and its interaction with an ftsz fragment revealed by X-ray crystallography

1F46 · Cell division protein zipa: “The bacterial cell-division protein zipa and its interaction with an ftsz fragment revealed by X-ray…”. X-ray diffraction, 3 pockets (best druggability 0.67). MolNFT v1 #6160 on GenesisL1: 3D structure…

PDB: 1F46
Type: protein
Length: 279 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cell division protein zipa
UniProt: P77173
Pockets: 3 · best druggability 0.67

Structure

x-ray diffraction · 2 distinct chains · 35% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cell division protein zipa	protein	139	35% helix, 27% strand	P77173
B	Cell division protein zipa	protein	140	35% helix, 26% strand	P77173

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	320	0.67	0.82	28	empty
2	162	0.46	0.76	26	empty
3	135	0.43	0.76	18	empty

Interfaces

1 interface between chains.

A–B · 775 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

1F46 · The bacterial cell-division protein zipa and its interaction with an ftsz fragment… · the same entry in another collection · chain A against A, TM-score 1.00
P77173 · AlphaFold monomer V2.0 prediction for cell division protein zipa (P77173) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P77173
Elsewhere: RCSB PDB 1F46 · PDBe 1F46 · UniProt P77173

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