UniProt P77173
Cell division protein zipA (P77173)
Cell division protein zipA (UniProt P77173): 16 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P77173
- Protein
- Cell division protein zipA
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 8 · 4 records with a druggable one
Structures
17 records of P77173 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1F46 | The bacterial cell-division protein zipa and its interaction with an ftsz fragment revealed by… | x-ray diffraction | A, B | — | 3 (best 0.67) |
| 1F46 | The bacterial cell-division protein zipa and its interaction with an ftsz fragment revealed by… | x-ray diffraction | A, B | — | — |
| 1F47 | The bacterial cell-division protein zipa and its interaction with an ftsz fragment revealed by… | x-ray diffraction | B | — | 2 (best 0.38) |
| 1F47 | The bacterial cell-division protein zipa and its interaction with an ftsz fragment revealed by… | x-ray diffraction | B | — | — |
| 1F7W | Solution structure of C-terminal domain zipa | solution nmr | A | — | — |
| 1F7W | Solution structure of C-terminal domain zipa | solution nmr | A | — | — |
| 1F7X | Solution structure of C-terminal domain zipa | solution nmr | A | — | — |
| 1F7X | Solution structure of C-terminal domain zipa | solution nmr | A | — | — |
| 1S1J | Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1 | x-ray diffraction | A, B | IQZ | 1 (best 0.61) |
| 1S1J | Crystal structure of zipa in complex with indoloquinolizin inhibitor 1 | x-ray diffraction | A, B | — | — |
| 1S1S | Crystal Structure of ZipA in complex with indoloquinolizin 10b | x-ray diffraction | A, B | WAC | 1 (best 0.62) |
| 1S1S | Crystal structure of zipa in complex with indoloquinolizin 10B | x-ray diffraction | A, B | — | — |
| 1Y2F | Crystal Structure of ZipA with an inhibitor | x-ray diffraction | A | WAI | — |
| 1Y2F | Crystal structure of zipa with an inhibitor | x-ray diffraction | A | — | — |
| 1Y2G | Crystal STructure of ZipA in complex with an inhibitor | x-ray diffraction | A, B | CL3 | 1 (best 0.61) |
| 1Y2G | Crystal structure of zipa in complex with an inhibitor | x-ray diffraction | A, B | — | — |
| P77173 | AlphaFold monomer V2.0 prediction for cell division protein zipa (P77173) | predicted | A | — | — |
Ligands
- CL3 · N-methyl-N-[3-(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)phenyl]acetamide · in 1 record
- IQZ · (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one · in 1 record
- WAC · N-{3-[(12bS)-7-oxo-1,3,4,6,7,12b-hexahydroindolo[2,3-a]quinolizin-12(2H)-yl]propyl}propane-2-sulfonamide · in 1 record
- WAI · 4-{2-[4-(2-aminoethyl)piperazin-1-yl]pyridin-4-yl}-N-(3-chloro-4-methylphenyl)pyrimidin-2-amine · in 1 record
Experiment against prediction
- 1Y2G chain B against the predicted model P77173: TM-score 0.99, RMSD 0.40 Å
- 1Y2G chain B against the predicted model P77173: TM-score 0.99, RMSD 0.40 Å
- 1S1J chain B against the predicted model P77173: TM-score 0.99, RMSD 0.43 Å
- 1S1J chain B against the predicted model P77173: TM-score 0.99, RMSD 0.43 Å
- 1F46 chain B against the predicted model P77173: TM-score 0.99, RMSD 0.49 Å
- 1F46 chain B against the predicted model P77173: TM-score 0.99, RMSD 0.49 Å
- 1Y2G chain A against the predicted model P77173: TM-score 0.99, RMSD 0.57 Å
- 1Y2G chain A against the predicted model P77173: TM-score 0.99, RMSD 0.57 Å
- 1S1J chain A against the predicted model P77173: TM-score 0.99, RMSD 0.57 Å
- 1S1J chain A against the predicted model P77173: TM-score 0.99, RMSD 0.57 Å
Elsewhere
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