MolNFT v1 · #61196 · protein

Crystal structure of apo form (zinc removed) of the botulinum neurotoxin type C light chain

3DEB · Botulinum neurotoxin C1 light chain: “Crystal structure of apo form (zinc removed) of the botulinum neurotoxin type C light chain”. X-ray diffraction, 2 ligands (NA, CA), 4 pockets (best druggability 0.77). MolNFT v1 #61196 on…

PDB: 3DEB
Type: protein
Length: 432 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Botulinum neurotoxin C1 light chain
EC: 3.4.24.69
UniProt: P18640
Ligands: NA, CA
Pockets: 4 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Botulinum neurotoxin C1 light chain (EC 3.4.24.69)	protein	432	31% helix, 19% strand	P18640

Ligands and binding sites

NA · Sodium ion · metal · chains A
CA · Calcium ion · metal · chains A
FMT · Formic acid · additive · 7 copies · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	493	0.77	0.85	58	NA, FMT
2	103	0.44	0.79	22	empty
3	101	0.36	0.75	19	FMT
4	74	0.33	0.75	18	empty

Compared structures

3DEB · Crystal Structure of apo form (Zinc removed) of the Botulinum Neurotoxin Type C Light… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P18640
Elsewhere: RCSB PDB 3DEB · PDBe 3DEB · UniProt P18640

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.