MolNFT v1 · #61073 · protein

Crystal structure of D2 domain from human FGFR2

3DAR · Fibroblast growth factor receptor 2: “Crystal structure of D2 domain from human FGFR2”. X-ray diffraction. MolNFT v1 #61073 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3DAR
Type: protein
Length: 198 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibroblast growth factor receptor 2
EC: 2.7.10.1
UniProt: P21802

Structure

x-ray diffraction · 1 distinct chain · 9% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Fibroblast growth factor receptor 2 (EC 2.7.10.1)	protein	99	9% helix, 53% strand	P21802

Interfaces

1 interface between chains.

A–B · 534 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3DAR · Crystal structure of D2 domain from human FGFR2 · the same entry in another collection · chain A against A, TM-score 1.00
P21802 · AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 2 (P21802) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21802
Elsewhere: RCSB PDB 3DAR · PDBe 3DAR · UniProt P21802

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