MolNFT v1 · #6033 · protein
Structure of the viral serpin crma
1F0C · Ice inhibitor: “Structure of the viral serpin crma”. X-ray diffraction, 4 pockets (best druggability 0.49). MolNFT v1 #6033 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1F0C
- Type
- protein
- Length
- 333 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ice inhibitor
- UniProt
- P07385
- Pockets
- 4 · best druggability 0.49
Structure
x-ray diffraction · 2 distinct chains · 23% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ice inhibitor | protein | 297 | 25% helix, 41% strand | P07385 |
| B | Ice inhibitor | protein | 36 | 0% helix, 47% strand | P07385 |
Ligands and binding sites
- DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.49 | 0.77 | 16 | empty |
| 2 | 69 | 0.43 | 0.81 | 15 | empty |
| 3 | 86 | 0.37 | 0.76 | 19 | DTT |
| 4 | 55 | 0.29 | 0.75 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 2333 Ų buried · 38 hydrogen bonds · protein-protein
Compared structures
- 1F0C · Structure of the viral serpin crma · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07385
- Elsewhere: RCSB PDB 1F0C · PDBe 1F0C · UniProt P07385
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