MolNFT v1 · #59878 · protein
The crystallographic structure of the digestive lysozyme 2 from musca domestica at 1.9 ang.
3CB7 · Lys-rich lysozyme 2: “The crystallographic structure of the digestive lysozyme 2 from musca domestica at 1.9 ang.”. X-ray diffraction, 3 pockets (best druggability 0.47). MolNFT v1 #59878 on GenesisL1: 3D structure, binding sites…
- PDB
- 3CB7
- Type
- protein
- Length
- 252 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lys-rich lysozyme 2
- EC
- 3.2.1.17
- UniProt
- Q7YT17
- Pockets
- 3 · best druggability 0.47
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Lys-rich lysozyme 2 (EC 3.2.1.17) | protein | 126 | 44% helix, 7% strand | Q7YT17 |
Ligands and binding sites
- ACY · Acetic acid · additive · 3 copies · chains A, B
- IPA · Isopropyl alcohol · additive · 2 copies · chains A, B
- GOL · Glycerol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 132 | 0.47 | 0.78 | 24 | empty |
| 2 | 76 | 0.39 | 0.78 | 16 | ACY |
| 3 | 54 | 0.32 | 0.77 | 15 | IPA, ACY |
Interfaces
1 interface between chains.
- A–B · 888 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 3CB7 · The crystallographic structure of the digestive lysozyme 2 from Musca domestica at 1.9… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7YT17
- Elsewhere: RCSB PDB 3CB7 · PDBe 3CB7 · UniProt Q7YT17
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