MolNFT v1 · #59877 · protein

Crystal structure of the S. pombe peptidase homology domain of fact complex subunit SPT16 (form B)

3CB6: “Crystal structure of the S. pombe peptidase homology domain of fact complex subunit SPT16 (form B)”. X-ray diffraction, 7 pockets (best druggability 0.58). MolNFT v1 #59877 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3CB6
Type: protein
Length: 441 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fact complex subunit SPT16
UniProt: O94267
Pockets: 7 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fact complex subunit SPT16	protein	441	41% helix, 21% strand	O94267

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	303	0.58	0.78	39	empty
2	180	0.56	0.80	45	empty
3	123	0.49	0.79	18	empty
4	96	0.40	0.77	17	empty
5	95	0.37	0.75	19	empty

Compared structures

3CB6 · Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16… · the same entry in another collection · chain A against A, TM-score 1.00
O94267 · AlphaFold monomer V2.0 prediction for fact complex subunit SPT16 (O94267) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O94267
Elsewhere: RCSB PDB 3CB6 · PDBe 3CB6 · UniProt O94267

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