MolNFT v1 · #59224 · protein

Crystal structure of ADP-glucose pyrophosphorylase from agrobacterium tumefaciens

3BRK · Glucose-1-phosphate adenylyltransferase: “Crystal structure of ADP-glucose pyrophosphorylase from agrobacterium tumefaciens”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.61). MolNFT v1 #59224 on GenesisL1: 3D…

PDB: 3BRK
Type: protein
Length: 395 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucose-1-phosphate adenylyltransferase
EC: 2.7.7.27
UniProt: P39669
Ligands: SO4
Pockets: 3 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)	protein	395	26% helix, 30% strand	P39669

Ligands and binding sites

SO4 · Sulfate ion · ion · 3 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	405	0.61	0.76	56	empty
2	319	0.57	0.76	41	SO4
3	67	0.30	0.73	14	empty

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

3BRK · Crystal Structure of ADP-Glucose Pyrophosphorylase from Agrobacterium tumefaciens · the same entry in another collection · chain X against X, TM-score 1.00
P39669 · AlphaFold monomer V2.0 prediction for glucose-1-phosphate adenylyltransferase (P39669) · a predicted model of the same protein · chain X against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39669
Elsewhere: RCSB PDB 3BRK · PDBe 3BRK · UniProt P39669

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