MolNFT v1 · #58907 · protein

Crystal structure of the 25KDA subunit of human cleavage factor im with AP4A

3BHO · Cleavage and polyadenylation specificity factor subunit 5: “Crystal structure of the 25KDA subunit of human cleavage factor im with AP4A”. X-ray diffraction, 1 ligand (B4P), 1 pocket (best druggability 0.67). MolNFT v1 #58907 on…

PDB: 3BHO
Type: protein
Length: 203 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cleavage and polyadenylation specificity factor subunit 5
UniProt: O43809
Ligands: B4P
Pockets: 1 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cleavage and polyadenylation specificity factor subunit 5	protein	203	24% helix, 37% strand	O43809

Ligands and binding sites

B4P · Bis(adenosine)-5'-tetraphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	444	0.67	0.79	36	B4P

Compared structures

3BHO · Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im with Ap4A · the same entry in another collection · chain A against A, TM-score 1.00
O43809 · AlphaFold monomer V2.0 prediction for cleavage and polyadenylation specificity factor… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43809
Elsewhere: RCSB PDB 3BHO · PDBe 3BHO · UniProt O43809

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