Emre multidrug transporter in complex with P4P, P21 crystal form

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 0% strand (DSSP).

Ligands and binding sites

• P4P · Tetraphenylphosphonium · ligand · 2 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

2 interfaces between chains.

• C–D · 111 Ų buried · 0 hydrogen bonds · protein-protein
• A–B · 93 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

• 3B62 · EmrE multidrug transporter in complex with P4P, P21 crystal form · the same entry in another collection · chain D against D, TM-score 1.00
• P23895 · AlphaFold monomer V2.0 prediction for multidrug transporter emre (P23895) · a predicted model of the same protein · chain C against A, TM-score 0.75
• 2I68 · Cryo-EM based theoretical model structure of transmembrane domain of the… · a predicted model of the same protein · chain C against A, TM-score 0.58
• 2I68 · Cryo-EM based theoretical model structure of transmembrane domain of the… · a predicted model of the same protein · chain C against A, TM-score 0.58

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P23895
• Elsewhere: RCSB PDB 3B62 · PDBe 3B62 · UniProt P23895