MolNFT v1 · #5846 · protein
Sialidase, large 68KD form, complexed with galactose
1EUT: “Sialidase, large 68KD form, complexed with galactose”. X-ray diffraction, 1 ligand (NA), 6 pockets (best druggability 0.73). MolNFT v1 #5846 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1EUT
- Type
- protein
- Length
- 601 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sialidase
- EC
- 3.2.1.18
- UniProt
- Q02834
- Ligands
- NA
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sialidase (EC 3.2.1.18) | protein | 601 | 2% helix, 48% strand | Q02834 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 252 | 0.73 | 0.88 | 33 | empty |
| 2 | 101 | 0.42 | 0.77 | 18 | empty |
| 3 | 112 | 0.38 | 0.75 | 19 | empty |
| 4 | 140 | 0.38 | 0.73 | 21 | empty |
| 5 | 95 | 0.35 | 0.74 | 23 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02834
- Elsewhere: RCSB PDB 1EUT · PDBe 1EUT · UniProt Q02834
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