MolNFT v1 · #258966 · protein
AlphaFold monomer V2.0 prediction for sialidase (Q02834)
Q02834: “AlphaFold monomer V2.0 prediction for sialidase (Q02834)”. 6 pockets (best druggability 0.70). MolNFT v1 #258966 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q02834
- Type
- protein
- Length
- 647 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- Sialidase
- UniProt
- Q02834
- Pockets
- 6 · best druggability 0.70
Structure
1 distinct chain · 3% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sialidase | protein | 647 | 3% helix, 45% strand | Q02834 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 215 | 0.70 | 0.87 | 35 | empty |
| 2 | 541 | 0.61 | 0.75 | 71 | empty |
| 3 | 127 | 0.54 | 0.82 | 28 | empty |
| 4 | 120 | 0.46 | 0.78 | 19 | empty |
| 5 | 76 | 0.31 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 1EUU · Sialidase or neuraminidase, large 68KD form · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1EUU · Sialidase or neuraminidase, large 68KD form · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1EUT · Sialidase, large 68KD form, complexed with galactose · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1EUT · Sialidase, large 68KD form, complexed with galactose · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 2BZD · Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. · an experimental structure of the same protein · chain A against C, TM-score 0.92
- 2BZD · Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. · an experimental structure of the same protein · chain A against C, TM-score 0.92
- 1WCQ · Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1WCQ · Mutagenesis of the nucleophilic tyrosine in a bacterial sialidase to phenylalanine. · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 1W8O · Contribution of the active site aspartic acid to catalysis in the bacterial neuraminidase… · an experimental structure of the same protein · chain A against A, TM-score 0.91
- 1W8O · Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase… · an experimental structure of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02834
- Elsewhere: UniProt Q02834 · AlphaFold DB Q02834
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