MolNFT v1 · #58137 · protein

Crystal structure of the zrd-deleted mutant of tias in complex with agmatine

3AU7 · Putative uncharacterized protein: “Crystal structure of the zrd-deleted mutant of tias in complex with agmatine”. X-ray diffraction, 1 ligand (AG2), 3 pockets (best druggability 0.53). MolNFT v1 #58137 on GenesisL1: 3D structure…

PDB: 3AU7
Type: protein
Length: 355 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative uncharacterized protein
UniProt: O28025
Ligands: AG2
Pockets: 3 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative uncharacterized protein	protein	355	28% helix, 33% strand	O28025

Ligands and binding sites

AG2 · Agmatine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	237	0.53	0.77	35	AG2
2	90	0.38	0.76	16	empty
3	69	0.32	0.74	12	empty

Compared structures

3AU7 · Crystal structure of the ZRD-deleted mutant of TiaS in complex with agmatine · the same entry in another collection · chain A against A, TM-score 1.00
O28025 · AlphaFold monomer V2.0 prediction for TRNA(ILE2) 2-agmatinylcytidine synthetase tias… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O28025
Elsewhere: RCSB PDB 3AU7 · PDBe 3AU7 · UniProt O28025

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.