MolNFT v1 · #57387 · protein
Crystal structure of unphosphorylated P70S6K1 (form II)
3A61 · Ribosomal protein S6 kinase beta-1: “Crystal structure of unphosphorylated P70S6K1 (form II)”. X-ray diffraction, 1 ligand (STU), 1 pocket (best druggability 0.61). MolNFT v1 #57387 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3A61
- Type
- protein
- Length
- 254 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosomal protein S6 kinase beta-1
- EC
- 2.7.11.1
- UniProt
- P23443
- Ligands
- STU
- Pockets
- 1 · best druggability 0.61
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) | protein | 254 | 35% helix, 17% strand | P23443 |
Ligands and binding sites
- STU · Staurosporine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 251 | 0.61 | 0.80 | 30 | STU |
Compared structures
- 3A61 · Crystal structure of unphosphorylated p70S6K1 (Form II) · the same entry in another collection · chain A against A, TM-score 1.00
- P23443 · AlphaFold monomer V2.0 prediction for ribosomal protein S6 kinase beta-1 (P23443) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23443
- Elsewhere: RCSB PDB 3A61 · PDBe 3A61 · UniProt P23443
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