MolNFT v1 · #57267 · protein
Crystal structure of serine palmitoyltransferase from sphingobacterium multivorum with substrate L-serine
3A2B: “Crystal structure of serine palmitoyltransferase from sphingobacterium multivorum with substrate L-serine”. X-ray diffraction, 2 ligands (SER, PLP), 2 pockets (best druggability 0.49). MolNFT v1 #57267 on GenesisL1: 3D structure…
- PDB
- 3A2B
- Type
- protein
- Length
- 392 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serine palmitoyltransferase
- EC
- 2.3.1.50
- UniProt
- A7BFV6
- Ligands
- SER, PLP
- Pockets
- 2 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serine palmitoyltransferase (EC 2.3.1.50) | protein | 392 | 46% helix, 17% strand | A7BFV6 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 254 | 0.49 | 0.74 | 47 | SER, PLP |
| 2 | 69 | 0.28 | 0.72 | 19 | empty |
Compared structures
- 3A2B · Crystal Structure of Serine Palmitoyltransferase from Sphingobacterium multivorum with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A7BFV6
- Elsewhere: RCSB PDB 3A2B · PDBe 3A2B · UniProt A7BFV6
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