MolNFT v1 · #56908 · protein

Left handed rada

2ZUB · DNA repair and recombination protein rada: “Left handed rada”. X-ray diffraction, 6 pockets (best druggability 0.75). MolNFT v1 #56908 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2ZUB
Type: protein
Length: 580 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair and recombination protein rada
UniProt: Q55075
Pockets: 6 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	DNA repair and recombination protein rada	protein	290	41% helix, 20% strand	Q55075

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	765	0.75	0.80	67	empty
2	228	0.51	0.76	27	empty
3	103	0.48	0.80	21	empty
4	85	0.32	0.73	19	empty
5	74	0.30	0.73	16	empty

Interfaces

1 interface between chains.

A–B · 1089 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

2ZUB · Left handed RadA · the same entry in another collection · chain A against A, TM-score 1.00
Q55075 · AlphaFold monomer V2.0 prediction for DNA repair and recombination protein rada (Q55075) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q55075
Elsewhere: RCSB PDB 2ZUB · PDBe 2ZUB · UniProt Q55075

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