MolNFT v1 · #56842 · protein

TAMAVIDIN2, novel avidin-like biotin-binding proteins from an edible mushroom

2ZSC: “TAMAVIDIN2, novel avidin-like biotin-binding proteins from an edible mushroom”. X-ray diffraction, 2 ligands (BTN, MG), 2 pockets (best druggability 0.64). MolNFT v1 #56842 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2ZSC
Type: protein
Length: 246 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TAMAVIDIN2
UniProt: B9A0T7
Ligands: BTN, MG
Pockets: 2 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	TAMAVIDIN2	protein	123	8% helix, 53% strand	B9A0T7

Ligands and binding sites

BTN · Biotin · ligand · 2 copies · chains A, B
MG · Magnesium ion · metal · 3 copies · chains A, B
GOL · Glycerol · additive · 9 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	109	0.64	0.88	21	BTN
2	164	0.60	0.83	33	BTN

Interfaces

1 interface between chains.

A–B · 542 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

2ZSC · Tamavidin2, Novel Avidin-like Biotin-Binding Proteins from an Edible Mushroom · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B9A0T7
Elsewhere: RCSB PDB 2ZSC · PDBe 2ZSC · UniProt B9A0T7

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