MolNFT v1 · #56803 · protein
Crystal structure of a mutant PIN1 peptidyl-prolyl cis-trans isomerase
2ZR5 · Peptidyl-prolyl cis-trans isomerase nima-interacting 1: “Crystal structure of a mutant PIN1 peptidyl-prolyl cis-trans isomerase”. X-ray diffraction, 2 ligands (1PG, SO4), 1 pocket (best druggability 0.43). MolNFT v1 #56803 on…
- PDB
- 2ZR5
- Type
- protein
- Length
- 153 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidyl-prolyl cis-trans isomerase nima-interacting 1
- EC
- 5.2.1.8
- UniProt
- Q13526
- Ligands
- 1PG, SO4
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidyl-prolyl cis-trans isomerase nima-interacting 1 (EC 5.2.1.8) | protein | 153 | 25% helix, 22% strand | Q13526 |
Ligands and binding sites
- 1PG · 2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.43 | 0.77 | 20 | SO4 |
Compared structures
- 2ZR5 · Crystal structure of a mutant PIN1 peptidyl-prolyl cis-trans isomerase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13526
- Elsewhere: RCSB PDB 2ZR5 · PDBe 2ZR5 · UniProt Q13526
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