MolNFT v1 · #56311 · protein
Crystal structure of tetr family transcription regulator SCO0332
2ZB9 · Putative transcriptional regulator: “Crystal structure of tetr family transcription regulator SCO0332”. X-ray diffraction, 3 pockets (best druggability 0.71). MolNFT v1 #56311 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2ZB9
- Type
- protein
- Length
- 370 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative transcriptional regulator
- UniProt
- Q9RK47
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative transcriptional regulator | protein | 188 | 77% helix, 0% strand | Q9RK47 |
| B | Putative transcriptional regulator | protein | 182 | 70% helix, 0% strand | Q9RK47 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 54 | 0.71 | 0.98 | 16 | empty |
| 2 | 67 | 0.35 | 0.77 | 19 | empty |
| 3 | 50 | 0.34 | 0.79 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 2023 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
- 2ZB9 · Crystal structure of TetR family transcription regulator SCO0332 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9RK47
- Elsewhere: RCSB PDB 2ZB9 · PDBe 2ZB9 · UniProt Q9RK47
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