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Crystal structure of tetr family transcription regulator SCO0332

Analyse Crystal structure of tetr family transcription regulator SCO0332 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2ZB9
Type
protein
Length
370 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Putative transcriptional regulator
UniProt
Q9RK47
Pockets
3 · best druggability 0.71

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APutative transcriptional regulatorprotein18877% helix, 0% strandQ9RK47
BPutative transcriptional regulatorprotein18270% helix, 0% strandQ9RK47

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1540.710.9816empty
2670.350.7719empty
3500.340.7915empty

Interfaces

1 interface between chains.

  • A–B · 2023 Ų buried · 28 hydrogen bonds · protein-protein

Compared structures

  • 2ZB9 · Crystal structure of TetR family transcription regulator SCO0332 · the same entry in another collection · chain A against A, TM-score 1.00

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