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MolNFT v1 · #56166 · protein

Crystal structure of the UFC1, UFM1 conjugating enzyme 1

2Z6O · UFM1-conjugating enzyme 1: “Crystal structure of the UFC1, UFM1 conjugating enzyme 1”. X-ray diffraction, 1 ligand (MG), 3 pockets (best druggability 0.48). MolNFT v1 #56166 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
2Z6O
Type
protein
Length
166 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
UFM1-conjugating enzyme 1
EC
6.3.2.19
UniProt
Q9Y3C8
Ligands
MG
Pockets
3 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AUFM1-conjugating enzyme 1 (EC 6.3.2.19)protein16640% helix, 19% strandQ9Y3C8

Ligands and binding sites

  • MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1850.480.8219empty
2890.370.7618empty
3910.320.7322empty

Compared structures

  • 2Z6O · Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y3C8 · AlphaFold monomer V2.0 prediction for ubiquitin-fold modifier- conjugating enzyme 1… · a predicted model of the same protein · chain A against A, TM-score 0.94

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