UniProt Q9Y3C8
Ubiquitin-fold modifier-conjugating enzyme 1 (Q9Y3C8)
Ubiquitin-fold modifier-conjugating enzyme 1 (UniProt Q9Y3C8): 14 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3C8
- Protein
- Ubiquitin-fold modifier-conjugating enzyme 1
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 14 · 2 records with a druggable one
Structures
15 records of Q9Y3C8 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2K07 | Solution NMR structure of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1).… | solution nmr | A | — | — |
| 2K07 | Solution NMR structure of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1).… | solution nmr | A | — | — |
| 2Z6O | Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 | x-ray diffraction | A | — | — |
| 2Z6O | Crystal structure of the UFC1, UFM1 conjugating enzyme 1 | x-ray diffraction | A | — | — |
| 2Z6P | Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 | x-ray diffraction | A | — | — |
| 2Z6P | Crystal structure of the UFC1, UFM1 conjugating enzyme 1 | x-ray diffraction | A | — | — |
| 3EVX | Crystal structure of the human E2-like ubiquitin-fold modifier conjugating enzyme 1 (Ufc1).… | x-ray diffraction | A, B, C, D | — | — |
| 3EVX | Crystal structure of the human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1).… | x-ray diffraction | A, B, C, D | — | — |
| 7NVJ | Crystal structure of UFC1 Y110A & F121A | x-ray diffraction | AAA | — | 1 (best 0.31) |
| 7NVK | Crystal structure of UBA5 fragment fused to the N-terminus of UFC1 | x-ray diffraction | AAA | — | 1 (best 0.35) |
| 7NW1 | Crystal structure of UFC1 in complex with UBA5 | x-ray diffraction | AAA, BBB | — | 5 (best 0.56) |
| 7OVC | Structure of the human UFC1 protein in complex with the UBA5 C-terminal UFC1-binding motif. | solution nmr | A | — | 2 (best 0.42) |
| 7OVC | Structure of the human UFC1 protein in complex with the UBA5 C- terminal UFC1-binding motif. | solution nmr | A | — | — |
| 8BZR | UFC1-UFM1 conjugate | x-ray diffraction | A | — | 2 (best 0.62) |
| Q9Y3C8 | AlphaFold monomer V2.0 prediction for ubiquitin-fold modifier- conjugating enzyme 1 (Q9Y3C8) | predicted | A | — | 3 (best 0.41) |
Experiment against prediction
- 3EVX chain A against the predicted model Q9Y3C8: TM-score 0.98, RMSD 0.64 Å
- 3EVX chain A against the predicted model Q9Y3C8: TM-score 0.98, RMSD 0.64 Å
- 8BZR chain A against the predicted model Q9Y3C8: TM-score 0.97, RMSD 0.92 Å
- 2Z6P chain A against the predicted model Q9Y3C8: TM-score 0.96, RMSD 1.54 Å
- 2Z6P chain A against the predicted model Q9Y3C8: TM-score 0.96, RMSD 1.54 Å
- 7NW1 chain AAA against the predicted model Q9Y3C8: TM-score 0.95, RMSD 1.39 Å
- 7NVJ chain AAA against the predicted model Q9Y3C8: TM-score 0.95, RMSD 1.62 Å
- 2Z6O chain A against the predicted model Q9Y3C8: TM-score 0.94, RMSD 1.75 Å
- 2Z6O chain A against the predicted model Q9Y3C8: TM-score 0.94, RMSD 1.75 Å
- 7NVK chain AAA against the predicted model Q9Y3C8: TM-score 0.84, RMSD 1.44 Å
Elsewhere
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