GL1X · GenesisL1 explorer

MolNFT v1 · #56091 · protein

Solution structure of the discoidin domain of DDR2

2Z4F · Discoidin domain-containing receptor 2: “Solution structure of the discoidin domain of DDR2”. Solution nmr, 1 pocket (best druggability 0.71). MolNFT v1 #56091 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2Z4F
Type
protein
Length
161 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Discoidin domain-containing receptor 2
EC
2.7.10.1
UniProt
Q16832
Pockets
1 · best druggability 0.71

Structure

solution nmr · 1 distinct chain · 0% helix, 40% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADiscoidin domain-containing receptor 2 (EC 2.7.10.1)protein1610% helix, 40% strandQ16832

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1630.710.9721empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 2Z4F · Solution structure of the Discoidin Domain of DDR2 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q16832 · AlphaFold monomer V2.0 prediction for discoidin domain-containing receptor 2 (Q16832) · a predicted model of the same protein · chain A against A, TM-score 0.87

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