MolNFT v1 · #55897 · protein
Crystal structure of the oxygenase component (hpab) of 4- hydroxyphenylacetate 3-monooxygenase complexed with FAD
2YYI · 4-hydroxyphenylacetate-3-hydroxylase: “Crystal structure of the oxygenase component (hpab) of 4- hydroxyphenylacetate 3-monooxygenase complexed with…”. X-ray diffraction, 2 ligands (FAD, SO4), 1 pocket (best druggability 0.75).…
- PDB
- 2YYI
- Type
- protein
- Length
- 474 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 4-hydroxyphenylacetate-3-hydroxylase
- EC
- 1.14.13.3
- UniProt
- Q5SJP8
- Ligands
- FAD, SO4
- Pockets
- 1 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 4-hydroxyphenylacetate-3-hydroxylase (EC 1.14.13.3) | protein | 474 | 54% helix, 15% strand | Q5SJP8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 821 | 0.75 | 0.79 | 56 | FAD |
Compared structures
- 2YYI · Crystal structure of the oxygenase component (HpaB) of 4-hydroxyphenylacetate… · the same entry in another collection · chain A against A, TM-score 1.00
- Q5SJP8 · AlphaFold monomer V2.0 prediction for 4-hydroxyphenylacetate 3-monooxygenase oxygenase… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SJP8
- Elsewhere: RCSB PDB 2YYI · PDBe 2YYI · UniProt Q5SJP8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.