MolNFT v1 · #55821 · protein

Crystal structure analysis of the 4-hydroxy-2-oxoglutarate ALDOLASE/2- deydro-3-deoxyphosphogluconate aldolase from TTHB1

2YW4 · 4-hydroxy-2-oxoglutarate ALDOLASE/2-deydro-3…: “Crystal structure analysis of the 4-hydroxy-2-oxoglutarate ALDOLASE/2- deydro-3-deoxyphosphogluconate…”. X-ray diffraction, 3 pockets (best druggability 0.38). MolNFT v1 #55821 on…

PDB: 2YW4
Type: protein
Length: 200 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 4-hydroxy-2-oxoglutarate ALDOLASE/2-deydro-3- deoxyphosphogluconate aldolase
EC: 4.1.2.14
UniProt: Q53W90
Pockets: 3 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	4-hydroxy-2-oxoglutarate ALDOLASE/2-deydro-3- deoxyphosphogluconate aldolase (EC 4.1.2.14)	protein	200	45% helix, 18% strand	Q53W90

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.38	0.78	16	empty
2	51	0.31	0.77	21	empty
3	61	0.31	0.75	17	empty

Compared structures

2YW4 · Crystal Structure Analysis of the 4-hydroxy-2-oxoglutarate… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53W90
Elsewhere: RCSB PDB 2YW4 · PDBe 2YW4 · UniProt Q53W90

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