Research workbench
Crystal structure analysis of the 4-hydroxy-2-oxoglutarate ALDOLASE/2- deydro-3-deoxyphosphogluconate aldolase from TTHB1
Analyse Crystal structure analysis of the 4-hydroxy-2-oxoglutarate ALDOLASE/2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YW4
- Type
- protein
- Length
- 200 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 4-hydroxy-2-oxoglutarate ALDOLASE/2-deydro-3- deoxyphosphogluconate aldolase
- EC
- 4.1.2.14
- UniProt
- Q53W90
- Pockets
- 3 · best druggability 0.38
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 4-hydroxy-2-oxoglutarate ALDOLASE/2-deydro-3- deoxyphosphogluconate aldolase (EC 4.1.2.14) | protein | 200 | 45% helix, 18% strand | Q53W90 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.38 | 0.78 | 16 | empty |
| 2 | 51 | 0.31 | 0.77 | 21 | empty |
| 3 | 61 | 0.31 | 0.75 | 17 | empty |
Compared structures
- 2YW4 · Crystal Structure Analysis of the 4-hydroxy-2-oxoglutarate… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q53W90
- Elsewhere: RCSB PDB 2YW4 · PDBe 2YW4 · UniProt Q53W90
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