MolNFT v1 · #55715 · protein

Solution structure of the chimera of the ptb domain of snt-2 and 19- residue peptide (aa 1571-1589) of halk

2YT2 · Fibroblast growth factor receptor substrate 3 and ALK…: “Solution structure of the chimera of the ptb domain of snt-2 and 19- residue peptide (aa 1571-1589) of halk”. Solution nmr, 2 pockets (best druggability 0.41). MolNFT v1…

PDB: 2YT2
Type: protein
Length: 153 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor
UniProt: O43559, Q9UM73
Pockets: 2 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 11% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor	protein	153	11% helix, 27% strand	O43559, Q9UM73

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	110	0.41	0.76	17	empty
2	52	0.30	0.76	14	empty

Compared structures

2YT2 · Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa… · the same entry in another collection · chain A against A, TM-score 1.00
O43559 · AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor substrate 3… · a predicted model of the same protein · chain A against A, TM-score 0.69
Q9UM73 · AlphaFold monomer V2.0 prediction for ALK tyrosine kinase receptor (Q9UM73) · a predicted model of the same protein · chain A against A, TM-score 0.32

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43559
Every structure of UniProt Q9UM73
Elsewhere: RCSB PDB 2YT2 · PDBe 2YT2 · UniProt O43559 · UniProt Q9UM73

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