MolNFT v1 · #55712 · protein
Solution structure of the chimera of the C-terminal pid domain of FE65L and the C-terminal tail peptide of app
2YSZ · Amyloid beta A4 precursor protein-binding family B member 2…: “Solution structure of the chimera of the C-terminal pid domain of FE65L and the C-terminal tail peptide of app”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT…
- PDB
- 2YSZ
- Type
- protein
- Length
- 185 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Amyloid beta A4 precursor protein-binding family B member 2 and amyloid beta A4 protein
- UniProt
- Q9DBR4, P12023
- Pockets
- 1 · best druggability 0.31
Structure
solution nmr · 1 distinct chain · 18% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Amyloid beta A4 precursor protein-binding family B member 2 and amyloid beta A4 protein | protein | 185 | 18% helix, 28% strand | Q9DBR4, P12023 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.31 | 0.76 | 17 | empty |
Compared structures
- 2YSZ · Solution structure of the chimera of the C-terminal PID domain of Fe65L and the… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9DBR4 · AlphaFold monomer V2.0 prediction for amyloid-beta A4 precursor protein-binding family B… · a predicted model of the same protein · chain A against A, TM-score 0.67
- P12023 · AlphaFold monomer V2.0 prediction for amyloid-beta A4 protein (P12023) · a predicted model of the same protein · chain A against A, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9DBR4
- Every structure of UniProt P12023
- Elsewhere: RCSB PDB 2YSZ · PDBe 2YSZ · UniProt Q9DBR4 · UniProt P12023
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