UniProt P12023
Amyloid-beta protein 40 (P12023)
Amyloid-beta protein 40 (UniProt P12023): 15 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12023
- Protein
- Amyloid-beta protein 40
- Experimental structures
- 15
- Predicted models
- 1
Structures
16 records of P12023 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ROZ | Structure of the C-terminal PID Domain of Fe65L1 Complexed with the Cytoplasmic Tail of APP Reveals… | solution nmr | A | — | — |
| 2ROZ | Structure of the C-terminal pid domain of FE65L1 complexed with the cytoplasmic tail of app reveals… | solution nmr | A | — | — |
| 2YSZ | Solution structure of the chimera of the C-terminal PID domain of Fe65L and the C-terminal tail… | solution nmr | A | — | — |
| 2YSZ | Solution structure of the chimera of the C-terminal pid domain of FE65L and the C-terminal tail… | solution nmr | A | — | — |
| 2YT0 | Solution structure of the chimera of the C-terminal tail peptide of APP and the C-terminal PID… | solution nmr | A | — | — |
| 2YT0 | Solution structure of the chimera of the C-terminal tail peptide of app and the C-terminal pid… | solution nmr | A | — | — |
| 2YT1 | Solution structure of the chimera of the C-terminal tail peptide of APP and the C-terminal PID… | solution nmr | A | — | — |
| 2YT1 | Solution structure of the chimera of the C-terminal tail peptide of app and the C-terminal pid… | solution nmr | A | — | — |
| 4YN0 | Crystal structure of APP E2 domain in complex with DR6 CRD domain | x-ray diffraction | B | — | — |
| 4YN0 | Crystal structure of app E2 domain in complex with DR6 crd domain | x-ray diffraction | B | — | — |
| 5MYK | Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with murine Abeta-pE3-18PEGb | x-ray diffraction | C | — | — |
| 5MYK | Structure of pyroglutamate-abeta-specific Fab C#17 in complex with murine abeta-PE3-18PEGB | x-ray diffraction | C | — | — |
| 7MRN | Mouse CNTN5 app complex | x-ray diffraction | C, D | — | — |
| 8BG9 | Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta | electron microscopy | A, B | — | — |
| 8S4Y | Crystal structure of an APP-talin (F2F3) chimera | x-ray diffraction | A | — | — |
| P12023 | AlphaFold monomer V2.0 prediction for amyloid-beta A4 protein (P12023) | predicted | A | — | — |
Experiment against prediction
- 7MRN chain C against the predicted model P12023: TM-score 0.99, RMSD 0.46 Å
- 7MRN chain D against the predicted model P12023: TM-score 0.98, RMSD 0.70 Å
- 4YN0 chain B against the predicted model P12023: TM-score 0.88, RMSD 2.32 Å
- 4YN0 chain B against the predicted model P12023: TM-score 0.88, RMSD 2.32 Å
- 2YT0 chain A against the predicted model Q9DBR4: TM-score 0.72, RMSD 3.39 Å
- 2YT0 chain A against the predicted model Q9DBR4: TM-score 0.72, RMSD 3.39 Å
- 5MYK chain C against the predicted model P12023: TM-score 0.70, RMSD 0.36 Å
- 5MYK chain C against the predicted model P12023: TM-score 0.70, RMSD 0.36 Å
- 2YSZ chain A against the predicted model Q9DBR4: TM-score 0.67, RMSD 1.83 Å
- 2YSZ chain A against the predicted model Q9DBR4: TM-score 0.67, RMSD 1.83 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.