MolNFT v1 · #55632 · protein

Solution structure of the first cadherin domain from human desmoglein- 2

2YQG · Desmoglein-2: “Solution structure of the first cadherin domain from human desmoglein- 2”. Solution nmr, 1 pocket (best druggability 0.45). MolNFT v1 #55632 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2YQG
Type: protein
Length: 123 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Desmoglein-2
UniProt: Q14126
Pockets: 1 · best druggability 0.45

Structure

solution nmr · 1 distinct chain · 6% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Desmoglein-2	protein	123	6% helix, 35% strand	Q14126

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	183	0.45	0.74	29	empty

Compared structures

2YQG · Solution structure of the first cadherin domain from human Desmoglein-2 · the same entry in another collection · chain A against A, TM-score 1.00
Q14126 · AlphaFold monomer V2.0 prediction for desmoglein-2 (Q14126) · a predicted model of the same protein · chain A against A, TM-score 0.77

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14126
Elsewhere: RCSB PDB 2YQG · PDBe 2YQG · UniProt Q14126

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