MolNFT v1 · #55629 · protein

Solution structure of the fifth bromodomain from mouse polybromo-1

2YQD: “Solution structure of the fifth bromodomain from mouse polybromo-1”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1 #55629 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2YQD
Type: protein
Length: 120 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polybromo-1
UniProt: Q8BSQ9
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 55% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polybromo-1	protein	120	55% helix, 2% strand	Q8BSQ9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.41	0.82	14	empty

Compared structures

2YQD · Solution structure of the fifth bromodomain from mouse polybromo-1 · the same entry in another collection · chain A against A, TM-score 1.00
Q8BSQ9 · AlphaFold monomer V2.0 prediction for protein polybromo-1 (Q8BSQ9) · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8BSQ9
Elsewhere: RCSB PDB 2YQD · PDBe 2YQD · UniProt Q8BSQ9

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