GL1X · GenesisL1 explorer

MolNFT v1 · #288896 · protein

AlphaFold monomer V2.0 prediction for protein polybromo-1 (Q8BSQ9)

Q8BSQ9: “AlphaFold monomer V2.0 prediction for protein polybromo-1 (Q8BSQ9)”. 15 pockets (best druggability 0.74). MolNFT v1 #288896 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q8BSQ9
Type
protein
Length
1,634 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x0356e122c1fF1b685d1f6dBC2f0B9adCa50B5286
Molecule
Protein polybromo-1
UniProt
Q8BSQ9
Pockets
15 · best druggability 0.74

Structure

1 distinct chain · 37% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein polybromo-1protein163437% helix, 11% strandQ8BSQ9

Pockets

15 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17100.740.8064empty
25180.650.7660empty
34300.620.7739empty
4850.530.8416empty
52170.520.7618empty

Compared structures

  • 2YQD · Solution structure of the fifth bromodomain from mouse polybromo-1 · an experimental structure of the same protein · chain A against A, TM-score 0.07
  • 2YQD · Solution structure of the fifth bromodomain from mouse polybromo-1 · an experimental structure of the same protein · chain A against A, TM-score 0.07

Analyse

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