MolNFT v1 · #55453 · protein
Crystal structure of the I-bar domain of IRSP53 (BAIAP2) in complex with an ehec derived tir peptide
2YKT · Brain-specific angiogenesis inhibitor 1-associated protein 2: “Crystal structure of the I-bar domain of IRSP53 (BAIAP2) in complex with an ehec derived tir peptide”. X-ray diffraction, 2 ligands (NH2, SO4), 1 pocket (best…
- PDB
- 2YKT
- Type
- protein
- Length
- 237 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Brain-specific angiogenesis inhibitor 1-associated protein 2; Translocated intimin…
- UniProt
- Q9UQB8, C6UYL8
- Ligands
- NH2, SO4
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 2 distinct chains · 87% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Brain-specific angiogenesis inhibitor 1-associated protein 2 | protein | 225 | 92% helix, 0% strand | Q9UQB8 |
| B | Translocated intimin receptor protein | protein | 12 | 0% helix, 0% strand | C6UYL8 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.36 | 0.76 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 600 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 2YKT · Crystal structure of the I-BAR domain of IRSp53 (BAIAP2) in complex with an EHEC derived… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UQB8 · AlphaFold monomer V2.0 prediction for brain-specific angiogenesis inhibitor 1-associated… · a predicted model of the same protein · chain A against A, TM-score 0.97
- C6UYL8 · AlphaFold monomer V2.0 prediction for translocated intimin receptor tir (C6UYL8) · a predicted model of the same protein · chain B against A, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UQB8
- Every structure of UniProt C6UYL8
- Elsewhere: RCSB PDB 2YKT · PDBe 2YKT · UniProt Q9UQB8 · UniProt C6UYL8
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