MolNFT v1 · #54636 · protein

Human lamin a coil 2B fragment

2XV5 · Lamin-A/C: “Human lamin a coil 2B fragment”. X-ray diffraction. MolNFT v1 #54636 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2XV5
Type: protein
Length: 114 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lamin-A/C
UniProt: P02545

Structure

x-ray diffraction · 1 distinct chain · 93% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Lamin-A/C	protein	57	93% helix, 0% strand	P02545

Interfaces

1 interface between chains.

A–B · 937 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

2XV5 · Human lamin A coil 2B fragment · the same entry in another collection · chain A against A, TM-score 1.00
P02545 · AlphaFold monomer V2.0 prediction for prelamin-A/C (P02545) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02545
Elsewhere: RCSB PDB 2XV5 · PDBe 2XV5 · UniProt P02545

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