MolNFT v1 · #54063 · protein
Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.
2XDG · Growth hormone-releasing hormone receptor: “Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.”. X-ray diffraction, 1 ligand (MG). MolNFT v1 #54063 on GenesisL1: 3D structure, binding…
- PDB
- 2XDG
- Type
- protein
- Length
- 178 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Growth hormone-releasing hormone receptor
- UniProt
- Q02643
- Ligands
- MG
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Growth hormone-releasing hormone receptor | protein | 89 | 28% helix, 22% strand | Q02643 |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 448 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 2XDG · Crystal structure of the extracellular domain of human growth hormone releasing hormone… · the same entry in another collection · chain A against A, TM-score 1.00
- Q02643 · AlphaFold monomer V2.0 prediction for growth hormone-releasing hormone receptor (Q02643) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02643
- Elsewhere: RCSB PDB 2XDG · PDBe 2XDG · UniProt Q02643
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