Research workbench
Crystal structure of the extracellular domain of human growth hormone releasing hormone receptor.
Analyse Crystal structure of the extracellular domain of human growth hormone releasing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XDG
- Type
- protein
- Length
- 178 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Growth hormone-releasing hormone receptor
- UniProt
- Q02643
- Ligands
- MG
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Growth hormone-releasing hormone receptor | protein | 89 | 28% helix, 22% strand | Q02643 |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 448 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 2XDG · Crystal structure of the extracellular domain of human growth hormone releasing hormone… · the same entry in another collection · chain A against A, TM-score 1.00
- Q02643 · AlphaFold monomer V2.0 prediction for growth hormone-releasing hormone receptor (Q02643) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02643
- Elsewhere: RCSB PDB 2XDG · PDBe 2XDG · UniProt Q02643
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