MolNFT v1 · #53978 · protein

DNA-binding domain from saccharomyces cerevisiae chromatin- remodelling protein CHD1

2XB0 · Chromo domain-containing protein 1: “DNA-binding domain from saccharomyces cerevisiae chromatin- remodelling protein CHD1”. X-ray diffraction, 1 ligand (CL), 2 pockets (best druggability 0.42). MolNFT v1 #53978 on GenesisL1: 3D…

PDB: 2XB0
Type: protein
Length: 233 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chromo domain-containing protein 1
EC: 3.6.1.-
UniProt: P32657
Ligands: CL
Pockets: 2 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 59% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Chromo domain-containing protein 1 (EC 3.6.1.-)	protein	233	59% helix, 2% strand	P32657

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains X
GOL · Glycerol · additive · 2 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	115	0.42	0.76	19	empty
2	57	0.29	0.75	13	empty

Compared structures

2XB0 · DNA-binding domain from Saccharomyces cerevisiae chromatin- remodelling protein Chd1 · the same entry in another collection · chain X against X, TM-score 1.00
P32657 · AlphaFold monomer V2.0 prediction for chromo domain-containing protein 1 (P32657) · a predicted model of the same protein · chain X against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32657
Elsewhere: RCSB PDB 2XB0 · PDBe 2XB0 · UniProt P32657

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