MolNFT v1 · #53548 · protein
Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122
2WY0: “Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122”. X-ray diffraction, 1 ligand (NA), 4 pockets (best druggability 0.46). MolNFT v1 #53548 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2WY0
- Type
- protein
- Length
- 424 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Angiotensinogen
- UniProt
- P11859
- Ligands
- NA
- Pockets
- 4 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Angiotensinogen | protein | 424 | 30% helix, 31% strand | P11859 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.46 | 0.79 | 24 | empty |
| 2 | 118 | 0.39 | 0.75 | 21 | NA |
| 3 | 115 | 0.39 | 0.75 | 20 | empty |
| 4 | 91 | 0.32 | 0.73 | 27 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2WY0 · Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 · the same entry in another collection · chain C against C, TM-score 1.00
- P11859 · AlphaFold monomer V2.0 prediction for angiotensinogen (P11859) · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11859
- Elsewhere: RCSB PDB 2WY0 · PDBe 2WY0 · UniProt P11859
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