MolNFT v1 · #53467 · protein
Mutation of THR163 to ser in human thymidine kinase shifts the specificity from thymidine towards the nucleoside analogue azidothymidine
2WVJ: “Mutation of THR163 to ser in human thymidine kinase shifts the specificity from thymidine towards the…”. X-ray diffraction. MolNFT v1 #53467 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2WVJ
- Type
- protein
- Length
- 1,290 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P04183
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, E, F | — | protein | 160 | — | P04183 |
| B | — | protein | 161 | — | P04183 |
| D | — | protein | 162 | — | P04183 |
| G | — | protein | 161 | — | P04183 |
| H | — | protein | 166 | — | P04183 |
Compared structures
- 2WVJ · Mutation of Thr163 to Ser in Human Thymidine Kinase Shifts the Specificity from Thymidine… · the same entry in another collection · chain F against F, TM-score 1.00
- P04183 · AlphaFold monomer V2.0 prediction for thymidine kinase, cytosolic (P04183) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04183
- Elsewhere: RCSB PDB 2WVJ · PDBe 2WVJ · UniProt P04183
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