MolNFT v1 · #53254 · protein
The novel beta-propeller of the btb-kelch protein KRP1 provides the binding site for lasp-1 that is necessary for pseudopodia extension
2WOZ · Kelch repeat and btb domain-containing protein 10: “The novel beta-propeller of the btb-kelch protein KRP1 provides the binding site for lasp-1 that is necessary…”. X-ray diffraction, 2 pockets (best druggability 0.78). MolNFT v1…
- PDB
- 2WOZ
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Kelch repeat and btb domain-containing protein 10
- UniProt
- Q9ER30
- Pockets
- 2 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Kelch repeat and btb domain-containing protein 10 | protein | 307 | 2% helix, 52% strand | Q9ER30 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 842 | 0.78 | 0.82 | 66 | empty |
| 2 | 51 | 0.49 | 0.87 | 14 | empty |
Compared structures
- 2WOZ · The novel beta-propeller of the BTB-Kelch protein Krp1 provides the binding site for… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9ER30 · AlphaFold monomer V2.0 prediction for kelch-like protein 41 (Q9ER30) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9ER30
- Elsewhere: RCSB PDB 2WOZ · PDBe 2WOZ · UniProt Q9ER30
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