MolNFT v1 · #53024 · protein

Crystal structures of the N-terminal intracellular domain of feob from klebsiella pneumoniae in GDP binding state

2WIB · Ferrous iron transport protein B: “Crystal structures of the N-terminal intracellular domain of feob from klebsiella pneumoniae in GDP binding…”. X-ray diffraction, 1 ligand (GDP), 3 pockets (best druggability 0.57). MolNFT v1…

PDB: 2WIB
Type: protein
Length: 518 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ferrous iron transport protein B
UniProt: A6TF32
Ligands: GDP
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ferrous iron transport protein B	protein	261	47% helix, 19% strand	A6TF32
B	Ferrous iron transport protein B	protein	257	43% helix, 19% strand	A6TF32

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	226	0.57	0.79	41	GDP
2	138	0.48	0.78	20	empty
3	65	0.34	0.77	12	empty

Interfaces

1 interface between chains.

A–B · 374 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

2WIB · Crystal Structures of the N-terminal Intracellular Domain of FeoB from Klebsiella… · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A6TF32
Elsewhere: RCSB PDB 2WIB · PDBe 2WIB · UniProt A6TF32

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