MolNFT v1 · #52806 · protein

Crystal structure of vioc in complex with (2S,3S)- hydroxyarginine

2WBQ · L-arginine beta-hydroxylase: “Crystal structure of vioc in complex with (2S,3S)- hydroxyarginine”. X-ray diffraction, 1 ligand (ZZU), 5 pockets (best druggability 0.73). MolNFT v1 #52806 on GenesisL1: 3D structure, binding sites and…

PDB: 2WBQ
Type: protein
Length: 332 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-arginine beta-hydroxylase
UniProt: Q6WZB0
Ligands: ZZU
Pockets: 5 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	L-arginine beta-hydroxylase	protein	332	33% helix, 23% strand	Q6WZB0

Ligands and binding sites

ZZU · (2S,3S)-3-hydroxyarginine · ligand · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.73	0.96	26	ACT, ZZU
2	71	0.50	0.85	22	empty
3	137	0.49	0.79	24	empty
4	90	0.36	0.75	21	empty
5	59	0.33	0.77	16	empty

Compared structures

2WBQ · Crystal structure of VioC in complex with (2S,3S)-hydroxyarginine · the same entry in another collection · chain A against A, TM-score 1.00
Q6WZB0 · AlphaFold monomer V2.0 prediction for alpha-ketoglutarate-dependent L-arginine… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6WZB0
Elsewhere: RCSB PDB 2WBQ · PDBe 2WBQ · UniProt Q6WZB0

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