MolNFT v1 · #52731 · protein
The crystal structure of SRP14 from the schizosaccharomyces pombe signal recognition particle
2W9J · Signal recognition particle subunit SRP14: “The crystal structure of SRP14 from the schizosaccharomyces pombe signal recognition particle”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #52731 on GenesisL1: 3D…
- PDB
- 2W9J
- Type
- protein
- Length
- 153 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Signal recognition particle subunit SRP14
- UniProt
- Q9P372
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal recognition particle subunit SRP14 | protein | 71 | 45% helix, 31% strand | Q9P372 |
| B | Signal recognition particle subunit SRP14 | protein | 82 | 46% helix, 28% strand | Q9P372 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.36 | 0.77 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 769 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (artifact).
Compared structures
- 2W9J · The crystal structure of SRP14 from the Schizosaccharomyces pombe signal recognition… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9P372 · AlphaFold monomer V2.0 prediction for signal recognition particle subunit SRP14 (Q9P372) · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9P372
- Elsewhere: RCSB PDB 2W9J · PDBe 2W9J · UniProt Q9P372
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