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The crystal structure of SRP14 from the schizosaccharomyces pombe signal recognition particle

Analyse The crystal structure of SRP14 from the schizosaccharomyces pombe signal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2W9J
Type
protein
Length
153 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Signal recognition particle subunit SRP14
UniProt
Q9P372
Pockets
1 · best druggability 0.36

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASignal recognition particle subunit SRP14protein7145% helix, 31% strandQ9P372
BSignal recognition particle subunit SRP14protein8246% helix, 28% strandQ9P372

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1740.360.7719empty

Interfaces

1 interface between chains.

  • A–B · 769 Ų buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (artifact).

Compared structures

  • 2W9J · The crystal structure of SRP14 from the Schizosaccharomyces pombe signal recognition… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9P372 · AlphaFold monomer V2.0 prediction for signal recognition particle subunit SRP14 (Q9P372) · a predicted model of the same protein · chain B against A, TM-score 0.94

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