MolNFT v1 · #52614 · protein
Saccharomyces cerevisiae GAS2P in complex with laminaripentaose
2W62 · Glycolipid-anchored surface protein 2: “Saccharomyces cerevisiae GAS2P in complex with laminaripentaose”. X-ray diffraction, 1 ligand (BGC), 4 pockets (best druggability 0.51). MolNFT v1 #52614 on GenesisL1: 3D structure, binding…
- PDB
- 2W62
- Type
- protein
- Length
- 436 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycolipid-anchored surface protein 2
- EC
- 2.4.1.-
- UniProt
- Q06135
- Ligands
- BGC
- Pockets
- 4 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycolipid-anchored surface protein 2 (EC 2.4.1.-) | protein | 436 | 34% helix, 17% strand | Q06135 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 225 | 0.51 | 0.75 | 30 | empty |
| 2 | 204 | 0.50 | 0.76 | 30 | BGC |
| 3 | 53 | 0.26 | 0.73 | 14 | empty |
| 4 | 58 | 0.26 | 0.72 | 18 | empty |
Modifications
Observed in the structure: 7 disulfide (disulfide).
Compared structures
- 2W62 · Saccharomyces cerevisiae Gas2p in complex with laminaripentaose · the same entry in another collection · chain A against A, TM-score 1.00
- Q06135 · AlphaFold monomer V2.0 prediction for 1,3-beta-glucanosyltransferase GAS2 (Q06135) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06135
- Elsewhere: RCSB PDB 2W62 · PDBe 2W62 · UniProt Q06135
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