MolNFT v1 · #52502 · protein

PCSK9-deltac D374A mutant bound to wt EGF-a of ldlr

2W2P: “PCSK9-deltac D374A mutant bound to wt EGF-a of ldlr”. X-ray diffraction. MolNFT v1 #52502 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2W2P
Type: protein
Length: 415 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q8NBP7, P01130

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	274	—	Q8NBP7
E	—	protein	48	—	P01130
P	—	protein	93	—	Q8NBP7

Compared structures

2W2P · PCSK9-deltaC D374A mutant bound to WT EGF-A of LDLR · the same entry in another collection · chain A against A, TM-score 1.00
P01130 · AlphaFold monomer V2.0 prediction for low-density lipoprotein receptor (P01130) · a predicted model of the same protein · chain E against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NBP7
Every structure of UniProt P01130
Elsewhere: RCSB PDB 2W2P · PDBe 2W2P · UniProt Q8NBP7 · UniProt P01130

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