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MolNFT v1 · #52117 · protein

The structure of the zinc finger from the human spliceosomal protein U1C

2VRD · U1 small nuclear ribonucleoprotein C: “The structure of the zinc finger from the human spliceosomal protein U1C”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.53). MolNFT v1 #52117 on GenesisL1: 3D structure, binding…

PDB
2VRD
Type
protein
Length
61 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
U1 small nuclear ribonucleoprotein C
UniProt
P09234
Ligands
ZN
Pockets
1 · best druggability 0.53

Structure

solution nmr · 1 distinct chain · 38% helix, 7% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AU1 small nuclear ribonucleoprotein Cprotein6138% helix, 7% strandP09234

Ligands and binding sites

  • ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12090.530.7722empty

Compared structures

  • 2VRD · The structure of the zinc finger from the human spliceosomal protein U1C · the same entry in another collection · chain A against A, TM-score 1.00
  • P09234 · AlphaFold monomer V2.0 prediction for U1 small nuclear ribonucleoprotein C (P09234) · a predicted model of the same protein · chain A against A, TM-score 0.50

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