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The structure of the zinc finger from the human spliceosomal protein U1C

Analyse The structure of the zinc finger from the human spliceosomal protein U1C in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2VRD
Type: protein
Length: 61 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U1 small nuclear ribonucleoprotein C
UniProt: P09234
Ligands: ZN
Pockets: 1 · best druggability 0.53

Structure

solution nmr · 1 distinct chain · 38% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	U1 small nuclear ribonucleoprotein C	protein	61	38% helix, 7% strand	P09234

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	209	0.53	0.77	22	empty

Compared structures

2VRD · The structure of the zinc finger from the human spliceosomal protein U1C · the same entry in another collection · chain A against A, TM-score 1.00
P09234 · AlphaFold monomer V2.0 prediction for U1 small nuclear ribonucleoprotein C (P09234) · a predicted model of the same protein · chain A against A, TM-score 0.50

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09234
Elsewhere: RCSB PDB 2VRD · PDBe 2VRD · UniProt P09234

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