MolNFT v1 · #51734 · protein
Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic metabolism in plants
2VG8 · Hydroquinone glucosyltransferase: “Characterization and engineering of the bifunctional N- and O-glucosyltransferase involved in xenobiotic…”. X-ray diffraction, 1 ligand (UDP), 6 pockets (best druggability 0.81). MolNFT v1 #51734…
- PDB
- 2VG8
- Type
- protein
- Length
- 465 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hydroquinone glucosyltransferase
- EC
- 2.4.1.218
- UniProt
- Q9M156
- Ligands
- UDP
- Pockets
- 6 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hydroquinone glucosyltransferase (EC 2.4.1.218) | protein | 465 | 45% helix, 13% strand | Q9M156 |
Ligands and binding sites
- UDP · Uridine-5'-diphosphate · ligand · chains A
- EDO · 1,2-ethanediol · additive · 9 copies · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 395 | 0.81 | 0.89 | 57 | UDP, TRS, EDO |
| 2 | 176 | 0.62 | 0.83 | 31 | EDO |
| 3 | 149 | 0.48 | 0.77 | 22 | empty |
| 4 | 186 | 0.47 | 0.75 | 23 | EDO |
| 5 | 96 | 0.36 | 0.74 | 18 | empty |
Compared structures
- 2VG8 · Characterization and engineering of the bifunctional N- and O- glucosyltransferase… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9M156 · AlphaFold monomer V2.0 prediction for udp-glycosyltransferase 72B1 (Q9M156) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9M156
- Elsewhere: RCSB PDB 2VG8 · PDBe 2VG8 · UniProt Q9M156
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.