MolNFT v1 · #51694 · protein

E. COLI glucosamine-6-P synthase

2VF4 · Glucosamine--fructose-6-phosphate aminotransferase: “E. COLI glucosamine-6-P synthase”. X-ray diffraction, 2 pockets (best druggability 0.42). MolNFT v1 #51694 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2VF4
Type: protein
Length: 359 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucosamine--fructose-6-phosphate aminotransferase
EC: 2.6.1.16
UniProt: P17169
Pockets: 2 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Glucosamine--fructose-6-phosphate aminotransferase (EC 2.6.1.16)	protein	359	48% helix, 14% strand	P17169

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	100	0.42	0.77	23	empty
2	120	0.42	0.76	22	empty

Compared structures

2VF4 · E. coli glucosamine-6-P synthase · the same entry in another collection · chain X against X, TM-score 1.00
P17169 · AlphaFold monomer V2.0 prediction for glutamine--fructose-6-phosphate aminotransferase… · a predicted model of the same protein · chain X against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P17169
Elsewhere: RCSB PDB 2VF4 · PDBe 2VF4 · UniProt P17169

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